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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFYVE16
All Species:
8.79
Human Site:
S635
Identified Species:
24.17
UniProt:
Q7Z3T8
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z3T8
NP_001098721.1
1539
168849
S635
S
E
I
T
N
Q
L
S
V
S
D
I
N
S
Q
Chimpanzee
Pan troglodytes
XP_001135982
1539
169040
S635
S
E
I
T
N
Q
L
S
V
S
D
I
N
S
Q
Rhesus Macaque
Macaca mulatta
XP_001110183
1540
169100
S636
S
E
I
T
N
E
L
S
V
S
D
T
N
S
Q
Dog
Lupus familis
XP_536310
1516
166814
K611
G
G
L
S
L
G
E
K
N
T
I
L
V
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q80U44
1528
166652
P623
P
D
I
R
D
E
L
P
V
P
S
I
K
T
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510291
1525
166161
I613
N
E
L
S
A
S
S
I
N
G
Q
T
I
H
A
Chicken
Gallus gallus
XP_424894
1103
120204
N259
S
E
T
L
Q
N
S
N
V
Y
D
P
K
D
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396901
1227
137615
D383
L
K
T
S
S
D
F
D
N
I
S
E
E
K
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781105
1601
173741
R652
D
K
E
H
Q
R
Q
R
N
T
S
H
Q
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
94.3
82.8
N.A.
73.4
N.A.
N.A.
59.5
27.3
N.A.
N.A.
N.A.
N.A.
30.1
N.A.
25.1
Protein Similarity:
100
99.3
96.3
88.7
N.A.
82
N.A.
N.A.
73.2
41.3
N.A.
N.A.
N.A.
N.A.
48.7
N.A.
43.9
P-Site Identity:
100
100
86.6
6.6
N.A.
33.3
N.A.
N.A.
6.6
26.6
N.A.
N.A.
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
93.3
33.3
N.A.
60
N.A.
N.A.
26.6
40
N.A.
N.A.
N.A.
N.A.
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
12
0
0
12
12
0
12
0
0
45
0
0
12
0
% D
% Glu:
0
56
12
0
0
23
12
0
0
0
0
12
12
12
12
% E
% Phe:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% F
% Gly:
12
12
0
0
0
12
0
0
0
12
0
0
0
0
0
% G
% His:
0
0
0
12
0
0
0
0
0
0
0
12
0
12
0
% H
% Ile:
0
0
45
0
0
0
0
12
0
12
12
34
12
0
0
% I
% Lys:
0
23
0
0
0
0
0
12
0
0
0
0
23
12
0
% K
% Leu:
12
0
23
12
12
0
45
0
0
0
0
12
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
34
12
0
12
45
0
0
0
34
0
0
% N
% Pro:
12
0
0
0
0
0
0
12
0
12
0
12
0
0
0
% P
% Gln:
0
0
0
0
23
23
12
0
0
0
12
0
12
0
56
% Q
% Arg:
0
0
0
12
0
12
0
12
0
0
0
0
0
0
0
% R
% Ser:
45
0
0
34
12
12
23
34
0
34
34
0
0
45
12
% S
% Thr:
0
0
23
34
0
0
0
0
0
23
0
23
0
12
0
% T
% Val:
0
0
0
0
0
0
0
0
56
0
0
0
12
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _